Ophiocordyceps sinensis. Yarsagumba. Yartsa gunbu. 3 Weeks course (21pcs, ~10-12g). Viagra of the Himalayas
Best quality Ophiocordyceps sinensis from Nepalese Himalayas.
1 Month(21 days) course. Always follow the 3 weeks use, 1 week rest cycle for better effects, even for longer courses. Each piece is ~0.5-0.6g and 4-6 cm in length. Eat 1 piece every morning for the duration of course for great improvements in energy, learning, memory, immune system, anti-aging, sexual function e.t.c. with this "Viagra of the Himalayas"
The fruiting body and attached mycelium of cordyceps have been used in Chinese culture and in traditional Chinese medicine for centuries. Cordyceps is valued for its activity in restoring energy, promoting longevity, and improving quality of life.
In traditional Chinese medicine (TCM), it is regarded as having an excellent balance of https://en.wikipedia.org/wiki/Yin_and_yang yin and yang as it is considered to be composed of both an animal and a vegetable.
O. sinensis parasitizes the moths of the https://en.wikipedia.org/wiki/Thitarodes Thitarodes genus in the ghost moth family, https://en.wikipedia.org/wiki/Hepialidae Hepialidae ; specifically species from the https://en.wikipedia.org/wiki/Tibetan_Plateau Tibetan Plateau , and the Himalayas. The fungus germinates in the living larva, kills and mummifies it, and then a dark brown stalk-like fruiting body which is a few centimeters long emerges from the corpse and stands upright.
It is known in English colloquially as caterpillar fungus , or by its more prominent names yartsa gunbu ( https://en.wikipedia.org/wiki/Tibetan_alphabet Tibetan : དབྱར་རྩྭ་དགུན་འབུ་ , https://en.wikipedia.org/wiki/Wylie_transliteration Wylie : dbyar rtswa dgun 'bu , literally "winter worm, summer grass"), or dōng chóng xià cǎo ( https://en.wikipedia.org/wiki/Chinese_language Chinese : 冬虫夏草 ).
O. sinensis is classified as a https://en.wikipedia.org/wiki/Medicinal_mushroom medicinal mushroom , and its use has a long history in https://en.wikipedia.org/wiki/Traditional_Chinese_medicine traditional Chinese medicine as well as https://en.wikipedia.org/wiki/Traditional_Tibetan_medicine traditional Tibetan medicine . The hand-collected, intact fungus-caterpillar body is valued by herbalists as medicine, and because of its cost, its use is also a status symbol.
Traditionally, cordyceps has been used in the elderly population to improve weakness, impotence, and fatigue associated with aging. Clinical studies have been conducted among elderly subjects; however, the methodology of such studies is often poorly documented. Improvements in self-reported symptoms have been described, as have increases in red blood cell superoxide dismutase activity and decreases in malondialdehyde levels. Other antioxidant effects, hydroxyl radical scavenging activity, and decreases in lipid peroxidation are thought to be responsible for the antiaging effects, as well as effects on the adrenergic and dopamine systems. Increases in learning and memory have been shown in experiments in aged mice.
Numerous in vitro and animal experiments have been conducted on aqueous and ethanol extracts of cordyceps, as well as with cordycepin and oxypiperazines extracted from the mycelium. The extracts enhanced cytokine activity and induced cell cycle arrest and apoptosis, thereby reducing tumor cell proliferation and enhancing survival times.
Limited clinical studies report subjective improvement of symptoms, increased tolerance of radiation and chemotherapy (possibly caused by enhanced immune function), and reduction in tumor size with coadministration of cordyceps. Animal experiments suggest a protective role for cordyceps in radiation- and chemotherapy-induced injury, with increased survival times demonstrated in mice.
Cordyceps has a long history of traditional medicinal use in heart disease. Adenosine and other nucleosides are thought to be responsible for the effects seen in animal studies. A vasodilatory action has been reported in anesthetized dogs, and hypotensive and vaso-relaxant effects have been demonstrated in rats. Reduced heart rate and restoration from arrhythmias have also been shown in animals. Long-term, open-label clinical studies in cardiac failure have described cordyceps' effect in improving cardiac function, arrhythmias, and overall quality of life, but are yet to be substantiated by large, high-quality clinical trials.
Fibrinolytic action of a cordyceps extract has been shown in vitro on bovine and human serum. Platelet aggregation has been inhibited in rabbits and in human platelets in vitro.
A positive effect on hyperlipidemia has also been reported in aqueous extracts of cordyceps.
Animal studies suggest cordyceps, particularly the polysaccharide extracts, decreases blood glucose levels by improving glucose metabolism and enhancing insulin sensitivity. Few clinical trials exist; however, 1 small (N = 20), randomized trial found that taking C. sinensis 3 g daily improved the blood sugar profile over placebo.
Hepatoprotective effects of cordyceps extracts have been demonstrated in animal models. Open-label clinical studies conducted in patients with active hepatitis and posthepatic cirrhosis reported improvements in liver function tests.
Immune system and anti-inflammatory effects
Aside from limited data from clinical studies conducted in renal transplant recipients and chronic hepatitis patients, the majority of studies have been conducted in vitro and in vivo using mice or rats and were directed at elucidating the mechanism of action for observed effects on the immune system. Different fractions of cordyceps extracts (either aqueous or ethanol based) appear to have different effects and, therefore, an immune-modulator function for cordyceps has been proposed. The effects of cordycepin and cordysinocan have been similarly evaluated.
In vitro effects include enhanced phagocytosis activity of macrophages, increased enzymatic activity of acid phosphatase, and induction of interleukin and tumor necrosis factor production. A decrease in cyclooxygenase-2 expression has also been demonstrated in vitro, but potential anti-inflammatory action has not been studied.
In mice, enhanced splenocyte proliferation, increased plasma corticosterone, decreased production of immunoglobulin E, and modulation of cytokine and CD4+ and CD8+ cell production were reported. Increased survival of cardiac grafts, suppression of the effects of streptococcal toxin on phagocytosis, increased survival from streptococcal group A infection, and attenuated disease severity in lupus-prone autoimmune mice were also described. Safety of cordyceps consumption with relation to the immune system was evaluated in mice, with an upregulation of the immune response demonstrated in the absence of splenomegaly.
Most clinical studies evaluating the effect of cordyceps on renal function are of poor methodology or use cordyceps in combination with other preparations. Clinical studies among elderly patients with long-term renal failure suggest improved renal function as demonstrated by increases in creatinine clearance, and decreases in blood urea nitrogen and serum creatinine. These findings are supported by histological studies in animals.
In patients in whom cordyceps was coadministered with amikacin and gentamicin, less nephrotoxicity was observed. In transplantation recipients, the incidence of nephrotoxicity was lower among cordyceps-treated patients, thus allowing for higher cyclosporin A dosing.
In vitro studies suggest aqueous extracts of C. sinensis have a stimulatory effect on ion transport in human airway epithelial cells, possibly because of cordycepin and adenosine. Animal studies suggest the observed effects on respiration are caused by enhanced oxygen utilization capacity, supporting the traditional use of cordyceps in Tibet and Nepal to offset altitude sickness. Clinical studies conducted in asthma, chronic obstructive pulmonary disease, and bronchitis have suggested efficacy for cordyceps. The methodology of these clinical studies is, however, not reported or is of open-label design, and cordyceps is often administered in combination with other preparations, making definitive statements about efficacy difficult.
Experiments in castrated rats showed a mild effect on sexual function. Decreases in erection and mount latency were demonstrated, but no effect on ejaculation latency was found; however, action on steroidogenesis and testosterone have been shown. In clinical studies in elderly populations, improved sexual drive and virility were reported.
Inhibition of osteoclast differentiation in mice has been described. Stimulation of erythropeiesis has been reported, as well as antibacterial, antifungal, and antimicrobial activity.
|Tags||ayurvedic, yarshagumba, xinganbao, cordyceps, caterpillarfungus, ayurveda, zhiling, yartsagunbu, yarsagumbu, cordycepssinensis|
|Categories||Tcm, Ayurvedic, Cordyceps, Ayurveda|
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